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Intended for US audiences only. Solo para personas de los Estados Unidos

Watch this instructive video where Dr. Veronica Flood discusses the benefits of prophylaxis for the treatment of von Willebrand disease (VWD) — who should consider it, the clinical data supporting the efficacy of prophylaxis, its risks and benefits, the selection of a dosing regimen, the importance of monitoring factor levels, the risk of inhibitor development, and unmet clinical and research needs.

Prophylaxis, or the proactive prevention of bleeding, has long been an accepted form of treatment in hemophilia. Now it is recommended in the treatment of VWD for people who experience severe bleeding, including joint bleeds, heavy menstrual bleeding, gastrointestinal bleeding, and more.1 Prophylaxis can improve quality of life, reducing the amount of bleeding, and possibly the amount of treatment required for individual bleeding events.1-4

VWD and Prophylaxis

Prophylaxis, or regular, proactive factor treatment to help reduce the frequency of bleeds by preventing them before they happen, can help people living with VWD manage their illness and stay ahead of symptoms.

Find out if prophylactic treatment is right for your VWD

Related Resources
  • Prophylaxis: Enhancing the Standard of Care for VWD (Infographic / Fact Sheet)
    In this on-demand webinar presented by Octapharma Senior Clinical Nurse Educator, Amber Federizo, DNP, you will learn about many myths about menstruation, the real facts and fundamentals of monthly bleeding, how bleeding disorders impact menstruation, why tracking your cycle is so important, and what should be considered when choosing methods for managing heavy periods.
  • Managing Severe Bleeding in VWD (Infographic / Fact Sheet)
    This infographic defines severe bleeding in von Willebrand disease (VWD), outlining its symptoms, and discusses treating severe bleeding with prophylactic therapy. It addresses the challenges of defining severe VWD, characteristics of those who may need prophylaxis, and the benefits prophylactic care can offer.
  • Von Willebrand Disease Prophylaxis — It Is Time! (Educational Article)
    This on-demand webinar presented by Octapharma resident hematologist, Claudio Sandoval, M.D., covers the signs and symptoms of VWD, common companion illnesses, therapy alternatives for on-demand (during a bleed) and prophylactic (before a bleed) treatments, as well as who can use prophylaxis and which therapies may be best suited.

References

1. Connell NT et al. Blood Adv. 2021;5(1):301-325.

2. Miesbach W, Berntorp E. Thromb Res. 2021;199:67-74.

3. James P et al. UpToDate. https://www.uptodate.com/contents/von-willebrand-disease-vwd-treatment-of-major-bleeding-and-major-surgery, (acc. 06/2025).

4. Du P et al. Clin Appl Thromb Hemost. 2022;28:1-8.

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